Related Parties (Details) - USD ($)	1 Months Ended	12 Months Ended
	Jul. 31, 2019	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Related parties
Issuance of common stock		$ 29,011,000
Deferred revenue		20,838,000	$ 18,748,000
Deferred revenue, noncurrent		913,000	854,000
Capitalized contract cost, Current		1,967,000	1,973,000
Capitalized contract cost, Noncurrent		$ 96,000	90,000
Common Stock Member
Related parties
Issuance of common stock (in shares)		2,337,405
Issuance of common stock		$ 0
License revenue
Related parties
Revenue		0	0
Deferred revenue, noncurrent		913,000	854,000
Capitalized contract costs			2,100,000	$ 2,100,000
Capitalized contract cost, Current		2,000,000.0	2,000,000.0
Capitalized contract cost, Noncurrent		96,000	90,000
Shenzhen Hepalink Pharmaceutical Group Co., Ltd.("Hepalink")
Related parties
Reduction to operating expenses on reimbursed to JV entity		(75,000)	(188,000,000,000)
Serum International B.V. ("SIBV") | License revenue
Related parties
Revenue		0	0
Deferred revenue		18,700,000	18,700,000
Deferred revenue, noncurrent		913,000	854,000,000,000
Capitalized contract costs		2,100,000
Capitalized contract cost, Current		2,000,000.0	2,000,000.0
Capitalized contract cost, Noncurrent		96,000	90,000
Serum International B.V. ("SIBV")
Related parties
Issuance of common stock (in shares)	801,820
Issuance of common stock	$ 10,000,000
Other receivables | Shenzhen Hepalink Pharmaceutical Group Co., Ltd.("Hepalink")
Related parties
Outstanding receivable for reimbursable expenses		$ 43,000	$ 3,000