Consolidated Statements of Changes in Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Common Stock Member Private placement	Common Stock Member ATM offering Agreement	Common Stock Member	Additional Paid-In Capital Private placement	Additional Paid-In Capital ATM offering Agreement	Additional Paid-In Capital	Accumulated Deficit	Private placement	ATM offering Agreement	Total
Balances at the beginning of the period at Dec. 31, 2019			$ 1			$ 104,404	$ (100,769)			$ 3,636
Balances at the beginning of the period (in shares) at Dec. 31, 2019			8,918,461
Changes in equity
Issuance of common stock				$ 5,807	$ 62			$ 5,807	$ 62
Issuance of common stock (in shares)	1,134,470	7,883
Issuance of common stock warrants in registered direct offering, net of issuance costs						2,005				2,005
Exercise of stock options						14				14
Exercise of stock options (in shares)			4,913
Stock-based compensation						2,128				2,128
Net loss							(22,333)			(22,333)
Balances at the end of the period at Dec. 31, 2020			$ 1			114,420	(123,102)			(8,681)
Balances at the end of the period (shares) at Dec. 31, 2020			10,065,727
Changes in equity
Issuance of common stock			$ 0			29,011				29,011
Issuance of common stock (in shares)			2,337,405						7,883
Issuance of common stock in connection with license agreement						6,460				6,460
Issuance of common stock in connection with license agreement (in shares)			884,956
Issuance of common stock for consulting services						33				33
Issuance of common stock for consulting services (in shares)			5,000
Issuance of common stock upon exercise of warrants			$ 1			3				4
Issuance of common stock upon exercise of warrants (in shares)			3,647,556
Deemed dividends (in shares)			759,389
Exercise of stock options						5				$ 5
Exercise of stock options (in shares)			1,559							1,559
Stock-based compensation						2,251				$ 2,251
Net loss							(42,193)			(42,193)
Balances at the end of the period at Dec. 31, 2021			$ 2			$ 152,183	$ (165,295)			$ (13,110)
Balances at the end of the period (shares) at Dec. 31, 2021			17,701,592