Balance Sheet Components - Licenses (Details) - The University of Alabama at Burmingham Research Foundation - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Minimum research funding agreed to provide	$ 50,000
Maximum contingent milestone payments	5,500,000
Milestone payments accrued	$ 0	$ 0
Reduction in payments for non-royalty income received for a combination product (as a percent)	50.00%
Minimum period of prior written notice for termination of agreement	90 days