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Summary of Significant Accounting Policies - Revenue Recognition (Details)
12 Months Ended
Dec. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
project
Dec. 31, 2016
USD ($)
Nov. 30, 2018
USD ($)
Summary of Significant Accounting Policies        
Revenue $ 2,757,000 $ 860,000    
Additional amount for extra work 440,000 440,000    
CF foundation        
Summary of Significant Accounting Policies        
Amount of award received for advance research on potential drugs     $ 2,902,097 $ 7,466,000
Grant        
Summary of Significant Accounting Policies        
Revenue 1,589,000 89,000    
Grant | CF foundation        
Summary of Significant Accounting Policies        
Revenue 1,589,000 89,000 $ 200,000  
Collaboration revenue        
Summary of Significant Accounting Policies        
Revenue $ 1,168,000 $ 771,000    
Research projects (In projects) | project   3