<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001274173-25-000334</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001274173</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001613780</issuerCik>
        <issuerName>DBV TECHNOLOGIES S.A.</issuerName>
        <issuerCusip>F2927N109</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>107 AVENUE DE LA REPUBLIQUE</com:street1>
          <com:city>CHATILLON</com:city>
          <com:stateOrCountry>I0</com:stateOrCountry>
          <com:zipCode>92320</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>JANUS HENDERSON GROUP PLC</reportingPersonName>
      <citizenshipOrOrganization>Y9</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>20469392</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>20469392</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>20469392</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.8</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>DBV TECHNOLOGIES S.A.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>107 AVENUE DE LA REPUBLIQUE
CHATILLON, FRANCE 92320</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Janus Henderson Group plc</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>201 Bishopsgate
EC2M 3AE, United Kingdom</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Y9</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>HC</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>JHIUS may be deemed to be the beneficial owner of 20,469,392 shares</amountBeneficiallyOwned>
        <classPercent>8.8</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>20469392</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>20469392</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
        <classOwnership5PercentOrLess>N</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>N</notApplicableFlag>
        <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>The interest of any one such Managed Portfolio does not exceed 5% of
the class of securities.</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
      </item6>
      <item7>
        <notApplicableFlag>N</notApplicableFlag>
        <subsidiaryIdentificationAndClassification>See Exihibit  99</subsidiaryIdentificationAndClassification>
      </item7>
      <item8>
        <notApplicableFlag>N</notApplicableFlag>
        <identificationAndClassificationOfGroupMembers>N/A</identificationAndClassificationOfGroupMembers>
      </item8>
      <item9>
        <notApplicableFlag>N</notApplicableFlag>
        <groupDissolutionNotice>N/A</groupDissolutionNotice>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Exhibit 24: Power of Attorney Exhibit 99: Item 7</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>JANUS HENDERSON GROUP PLC</reportingPersonName>
      <signatureDetails>
        <signature>Kristin Mariani</signature>
        <title>Head of North America Compliance, CCO</title>
        <date>01/08/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
