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Segment and Geographic Information - Segment Reporting (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Jan. 23, 2026
Jan. 24, 2025
Jan. 23, 2026
Jan. 24, 2025
Segment Reporting Information [Line Items]        
Net sales $ 9,017 $ 8,292 $ 26,557 $ 24,610
Cost of products sold, excluding amortization of intangible assets 3,261 2,779 9,323 8,485
Research and development expense 722 675 2,202 2,048
Selling, general, and administrative expense 2,956 2,717 8,727 8,129
Reportable segment operating profit 1,464 1,646 4,594 4,519
Other non-operating income, net 121 72 247 403
Amortization of intangible assets (441) (416) (1,364) (1,243)
Restructuring and associated costs (172)   (251)  
Certain litigation charges, net (62) (22) (89) (104)
Income before income taxes 1,404 1,540 4,302 4,367
Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 8,985 8,260 26,417 24,593
Cost of products sold, excluding amortization of intangible assets 3,173 2,748 9,197 8,350
Research and development expense 720 672 2,200 2,038
Selling, general, and administrative expense 2,897 2,701 8,591 8,067
Other segment items 3 (12) (17) (27)
Reportable segment operating profit 2,192 2,151 6,446 6,166
Segment reconciling items        
Segment Reporting Information [Line Items]        
Other adjustments     39 (90)
Currency and other (13) 4 (108) (44)
Interest expense, net (181) (179) (539) (555)
Other non-operating income, net 121 72 247 403
Amortization of intangible assets (441) (416) (1,364) (1,243)
Restructuring and associated costs (172) (46) (251) (154)
Acquisition and divestiture-related items (38) (28) (96) (15)
Certain litigation charges, net (62) (22) (89) (104)
Medical device regulations   (11)   (38)
Cardiovascular | Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 3,457 3,037 10,179 9,145
Cost of products sold, excluding amortization of intangible assets 1,159 964 3,426 3,013
Research and development expense 284 248 863 761
Selling, general, and administrative expense 1,129 1,010 3,331 3,009
Other segment items (14) (14) (45) (27)
Reportable segment operating profit 899 828 2,604 2,389
Neuroscience | Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 2,558 2,458 7,536 7,226
Cost of products sold, excluding amortization of intangible assets 815 712 2,308 2,108
Research and development expense 153 152 477 463
Selling, general, and administrative expense 841 820 2,546 2,462
Other segment items 12 12 23 19
Reportable segment operating profit 737 762 2,183 2,173
Medical Surgical | Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 2,173 2,072 6,428 6,196
Cost of products sold, excluding amortization of intangible assets 867 788 2,512 2,385
Research and development expense 174 164 523 496
Selling, general, and administrative expense 628 605 1,861 1,805
Other segment items 6 4 9 14
Reportable segment operating profit 499 512 1,523 1,496
Diabetes | Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 796 694 2,274 2,027
Cost of products sold, excluding amortization of intangible assets 332 284 951 844
Research and development expense 109 108 337 317
Selling, general, and administrative expense 300 266 853 790
Other segment items (2) (15) (3) (33)
Reportable segment operating profit 57 50 136 108
Other operating segment | Operating Segments        
Segment Reporting Information [Line Items]        
Net sales 32 32 101 106
Other adjustments     39 (90)
Reportable segment operating profit $ (1) $ 13 $ 18 $ 39