SCHEDULE 13G/A 0001437749-23-002597 0001613103 XXXXXXXX LIVE 3 Common Stock, Par Value $0.0001 Per Share 12/31/2025 0001814114 Orchestra BioMed Holdings, Inc. 68572M106 150 UNION SQUARE DRIVE NEW HOPE VA 18938 Rule 13d-1(c) Medtronic plc L2 0.00 10078625.00 0.00 10078625.00 10078625.00 17.8 OO Calculated based on 56,464,731 shares of Common Stock issued and outstanding as of November 6, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q filed November 10, 2025. Covidien Group S.a.r.l. N4 0.00 10078625.00 0.00 10078625.00 10078625.00 17.8 OO Calculated based on 56,464,731 shares of Common Stock issued and outstanding as of November 6, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q filed November 10, 2025. Orchestra BioMed Holdings, Inc. 150 UNION SQUARE DRIVE, NEW HOPE, VIRGINIA, 18938. Medtronic plc Covidien Group S.a.r.l. Medtronic plc: Building 2, Parkmore Business Park West, Galway, Ireland Covidien Group S.a.r.l., Ground Floor, Espace Monterery, 40 Av Monterey, L-2163 Luxembourg Medtronic plc: Ireland Covidien Group S.a.r.l.: Luxembourg Y See Cover Pages, Items 5 through 11. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Joint Filing Agreement between Medtronic plc and Covidien Group S.a.r.l., dated as of February 6, 2023, filed as Exhibit 1 to the Schedule 13G filed on February 6, 2023. Medtronic plc /s/ Brian Sandstron 02/27/2026 Covidien Group S.a.r.l. /s/ Salvador Sens 02/27/2026