X0306 4 2021-12-15 0001613103 Medtronic plc MDT 0001792380 Salmon Sean 710 MEDTRONIC PARKWAY LC300 MINNEAPOLIS MN 55432 1 EVP & Pres Diabetes/Cardiovasc Ordinary Shares 2021-12-15 4 F 0 89 104.94 D 33083 D The reported transaction involved the withholding of 89 shares of stock issuable upon the early vesting of an equal number of restricted stock units to pay taxes associated with the reporting person becoming retirement eligible. /s/ Thomas L. Osteraas, attorney-in-fact 2021-12-16