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Shareholders equity - Share capital (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Sep. 30, 2021
EUR (€)
shares
Apr. 30, 2021
EUR (€)
shares
Jan. 31, 2021
EUR (€)
shares
Jun. 30, 2021
EUR (€)
Jun. 30, 2021
EUR (€)
Jun. 30, 2022
EUR (€)
€ / shares
shares
Dec. 31, 2021
shares
Nov. 04, 2021
USD ($)
Sep. 30, 2021
$ / shares
Apr. 30, 2021
$ / shares
Mar. 31, 2020
USD ($)
Shareholders Equity                      
Authorized share capital           € 13,600,000          
Par value per share | € / shares           € 0.04          
Net proceeds from issuance of shares       € 82,601,000 € 85,254,000            
Shares issued in the period         € 85,254,000            
Eli Lilly and Company                      
Shareholders Equity                      
Net proceeds from issuance of shares € 23,223,000                    
Issue of ordinary shares (in shares) | shares 3,989,976                    
Share price | $ / shares                 $ 7.52    
Underwritten public offering                      
Shareholders Equity                      
Issue of ordinary shares (in shares) | shares   15,923,077                  
Share price | $ / shares                   $ 6.50  
Gross proceeds from issuance of shares   € 88,115,000                  
Transaction cost   5,499,000                  
Net proceeds   € 82,616,000                  
At The Market Offering                      
Shareholders Equity                      
Issue of ordinary shares (in shares) | shares     585,398                
Gross proceeds from issuance of shares     € 2,767,000                
Transaction cost     114,000                
Net proceeds     € 2,653,000                
Cantor Fitzgerald & Co | At The Market Offering                      
Shareholders Equity                      
Number of shares issued | shares           0          
Ordinary                      
Shareholders Equity                      
Number of shares outstanding | shares           74,865,381          
Maximum aggregate offering of ordinary shares | $               $ 300,000,000      
Number of shares authorised | shares           170,000,000          
Shares were issued and fully paid in cash | shares           71,362,088          
Treasury shares | shares           3,503,293 3,574,576        
Ordinary | Cantor Fitzgerald & Co | At The Market Offering                      
Shareholders Equity                      
Maximum aggregate offering of ordinary shares | $               $ 75,000,000      
Ordinary | Market offering program                      
Shareholders Equity                      
Maximum aggregate offering of ordinary shares | $                     $ 75,000,000
Preferred                      
Shareholders Equity                      
Number of shares authorised | shares           170,000,000