144 0001965525 XXXXXXXX LIVE 0001612042 Ascendis Pharma A/S 001-36815 TUBORG BOULEVARD 12 HELLERUP P7 1105 BP 45 70 22 22 44 IMANI SIHAM Director ORDINARY SHARES CITIGROUP GLOBAL MARKETS

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1800 435762.00 61977408 03/02/2026 NASDAQ ORDINARY SHARES 03/02/2026 RESTRICTED STOCK VESTING ASCENDIS PHARMA A/S N 2773 03/02/2026 COMPENSATION Y SECTION 3D BASED ON INDICATIVE MARKET PRICE 242.09. SHARES BEING SOLD FOR THE VESTING AND SETTLEMENT OF EQUITY AWARDS. UNDER SECURITIES TO BE SOLD DATE ACQUIRED ARE VARIOUS DATES.THE INTENDED NUMBER OF SHARES IS AN APPRROXIMATION DUE TO MARKET CONDITIONS. SALES ARE BEING PERFORMED OVER MULTIPLE DAYS.THESE ARE NON DISCRETIONARY TRANSACTIONS. THESE ARE BEING PERFORMED UNDER AN ESTABLISHED 10B51 PLAN 03/02/2026 09/05/2024 CONFORMED SIGNATURE ON FILE