Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	At-the-Market Program	March 2020 Offering	October 2020 Private Placement	February 2021 Offering	LPC Purchase Agreement	November 2021 Offering	Common Stock, $0.001 par value	Common Stock, $0.001 par value At-the-Market Program	Common Stock, $0.001 par value March 2020 Offering	Common Stock, $0.001 par value October 2020 Private Placement	Common Stock, $0.001 par value February 2021 Offering	Common Stock, $0.001 par value LPC Purchase Agreement	Common Stock, $0.001 par value November 2021 Offering	Additional Paid-In Capital	Additional Paid-In Capital At-the-Market Program	Additional Paid-In Capital March 2020 Offering	Additional Paid-In Capital October 2020 Private Placement	Additional Paid-In Capital February 2021 Offering	Additional Paid-In Capital LPC Purchase Agreement	Additional Paid-In Capital November 2021 Offering	Accumulated Deficit	Accumulated Other Comprehensive Loss
Beginning Balance at Dec. 31, 2019	$ 5,835							$ 1							$ 111,509							$ (104,773)	$ (902)
Beginning Balance, Shares at Dec. 31, 2019								877,672
Proceeds from the issuance of common stock		$ 5,043	$ 1,348	$ 2,791												$ 5,043	$ 1,348	$ 2,791
Proceeds from the issuance of common stock, Shares									232,526	178,776	187,646
Warrant issued			$ 842	$ 629													$ 842	$ 629
Share issuance costs	(819)														(819)
Settlement of restricted stock units, Shares								7,792
Reverse stock split round down								(50)
Stock-based compensation	2,529														2,529
Foreign currency translation adjustments	(197)																						(197)
Net loss	(14,130)																					(14,130)
Ending Balance at Dec. 31, 2020	3,871							$ 1							123,872							(118,903)	(1,099)
Ending Balance, Shares at Dec. 31, 2020								1,484,362
Proceeds from the issuance of common stock					$ 8,399	$ 577	$ 11,081					$ 1		$ 2					$ 8,398	$ 577	$ 11,079
Proceeds from the issuance of common stock, Shares												744,936	40,000	1,385,031
Warrant issued					$ 2,638														$ 2,638
Share issuance costs	(2,744)														(2,744)
Share issuance costs, Shares								31,958
Proceeds from the exercise of warrants	1,318														1,318
Proceeds from the exercise of warrants, Shares								81,895
Proceeds from the exercise of stock options	$ 2														2
Proceeds from the exercise of stock options, Shares	214							214
Settlement of restricted stock units, Shares								5,012
Issuance of shares to a consultant for services	$ 20														20
Issuance of shares to a consultant for services, Shares								1,929
Stock-based compensation	4,252														4,252
Stock-based compensation, Shares								5,337
Foreign currency translation adjustments	(26)																						(26)
Net loss	(18,132)																					(18,132)
Ending Balance at Dec. 31, 2021	$ 11,256							$ 4							$ 149,412							$ (137,035)	$ (1,125)
Ending Balance, Shares at Dec. 31, 2021								3,780,674