Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Revenue:
Total operating revenue	$ 522	$ 661
Cost of sales:
Cost of product sales	$ 298	$ 388
Type of Cost, Good or Service [Extensible List]	Product	Product
Gross profit	$ 224	$ 273
Operating expenses:
Research and development	5,990	4,582
Selling, general and administrative	12,176	9,714
Amortization expense	200	363
Total operating expenses	18,366	14,659
Operating loss	(18,142)	(14,386)
Other income:
Other income		63
Change in fair value of derivative financial instruments		4
Foreign exchange gain	10	189
Total other income	10	256
Net loss	(18,132)	(14,130)
Other comprehensive loss:
Foreign currency translation adjustments	(26)	(197)
Comprehensive loss	$ (18,158)	$ (14,327)
Net loss per share
Basic	$ (7.38)	$ (11.80)
Diluted	$ (7.38)	$ (11.80)
Weighted average shares outstanding
Basic	2,456,782	1,197,774
Diluted	2,456,782	1,197,774
Product
Revenue:
Total operating revenue	$ 493	$ 625
Franchise
Revenue:
Total operating revenue		9
License
Revenue:
Total operating revenue	$ 29	$ 27