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Condensed Consolidated Statement of Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Beginning balance at Dec. 31, 2018 $ (48,045) $ 41 $ 341,284 $ (389,370)  
Beginning balance, shares at Dec. 31, 2018   40,936,735      
Issuance of common stock upon exercise of stock options, value 120   120    
Issuance of common stock upon exercise of stock options, shares   38,125      
Issuance of common stock upon vesting of RSUs, net of tax withholdings 153   153    
Issuance of common stock upon vesting of RSUs, net of tax withholdings, shares   73,500      
Issuance of common stock under ESPP plan, value 207   207    
Issuance of common stock under ESPP plan, shares   46,472      
Stock-based compensation expense 2,065   2,065    
Net loss (24,333)     (24,333)  
Ending balance at Mar. 31, 2019 (69,833) $ 41 343,829 (413,703)  
Ending balance, shares at Mar. 31, 2019   41,094,832      
Beginning balance at Dec. 31, 2018 (48,045) $ 41 341,284 (389,370)  
Beginning balance, shares at Dec. 31, 2018   40,936,735      
Net loss (35,092)        
Ending balance at Jun. 30, 2019 (17,968) $ 70 406,424 (424,462)  
Ending balance, shares at Jun. 30, 2019   69,913,410      
Beginning balance at Mar. 31, 2019 (69,833) $ 41 343,829 (413,703)  
Beginning balance, shares at Mar. 31, 2019   41,094,832      
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs, value 60,527 $ 29 60,498    
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs, shares   28,818,578      
Stock-based compensation expense 2,097   2,097    
Net loss (10,759)     (10,759)  
Ending balance at Jun. 30, 2019 (17,968) $ 70 406,424 (424,462)  
Ending balance, shares at Jun. 30, 2019   69,913,410      
Beginning balance at Dec. 31, 2019 $ (48,324) $ 70 411,255 (459,649)  
Beginning balance, shares at Dec. 31, 2019 70,143,252 70,143,252      
Issuance of common stock from at the market equity offering $ 4,178 $ 1 4,177    
Issuance of common stock from at the market equity offering, shares   1,230,531      
Issuance of common stock upon exercise of stock options, value 60 $ 1 59    
Issuance of common stock upon exercise of stock options, shares   110,967      
Issuance of common stock upon vesting of RSUs, net of tax withholdings 120   120    
Issuance of common stock upon vesting of RSUs, net of tax withholdings, shares   110,000      
Issuance of common stock under ESPP plan, value 249   249    
Issuance of common stock under ESPP plan, shares   76,317      
Stock-based compensation expense 1,959   1,959    
Unrealized gain (loss) on investments (10)       $ (10)
Net loss (19,881)     (19,881)  
Ending balance at Mar. 31, 2020 (61,649) $ 72 417,819 (479,530) (10)
Ending balance, shares at Mar. 31, 2020   71,671,067      
Beginning balance at Dec. 31, 2019 $ (48,324) $ 70 411,255 (459,649)  
Beginning balance, shares at Dec. 31, 2019 70,143,252 70,143,252      
Issuance of common stock upon exercise of stock options, shares 141,281        
Net loss $ (40,595)        
Ending balance at Jun. 30, 2020 $ (65,575) $ 75 434,593 (500,244) 1
Ending balance, shares at Jun. 30, 2020 75,131,834 75,131,834      
Beginning balance at Mar. 31, 2020 $ (61,649) $ 72 417,819 (479,530) (10)
Beginning balance, shares at Mar. 31, 2020   71,671,067      
Issuance of common stock from at the market equity offering 14,848 $ 3 14,845    
Issuance of common stock from at the market equity offering, shares   3,430,453      
Issuance of common stock upon exercise of stock options, value 15   15    
Issuance of common stock upon exercise of stock options, shares   30,314      
Stock-based compensation expense 1,914   1,914    
Unrealized gain (loss) on investments 11       11
Net loss (20,714)     (20,714)  
Ending balance at Jun. 30, 2020 $ (65,575) $ 75 $ 434,593 $ (500,244) $ 1
Ending balance, shares at Jun. 30, 2020 75,131,834 75,131,834