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Income Taxes - Schedule of Reconciliation of U.S Federal Statutory Income Tax Rate to Company's Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]      
Federal statutory income tax rate (21.00%) (21.00%) (34.00%)
Research and development tax credits (5.80%) (7.20%) (7.70%)
State taxes, net of federal benefit (6.80%) (7.20%) (4.80%)
Stock-based compensation (1.70%) 2.00% 1.20%
Revaluation of preferred stock warrant liability     33.10%
Other (0.70%) 0.80% (0.30%)
Change in deferred tax asset valuation allowance 36.00% 32.60% 12.50%
Effective income tax rate 0.00% 0.00% 0.00%