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Commitments and Contingencies - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
Other Commitments [Line Items]          
Operating lease agreement expiration date     Jan. 31, 2018    
Indemnification Agreement [Member]          
Other Commitments [Line Items]          
Indemnification obligations accrued $ 0   $ 0   $ 0
Office and Laboratory Space [Member]          
Other Commitments [Line Items]          
Rental expense related to office and laboratory space $ 352,000 $ 118,000 $ 892,000 $ 343,000