Income Taxes - Schedule of Reconciliation of U.S Federal Statutory Income Tax Rate to Company's Effective Income Tax Rate (Detail)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	[1]	Dec. 31, 2022	[1]
Income Tax Disclosure [Abstract]
Federal statutory income tax rate	(21.00%)	(21.00%)		(21.00%)
Research and development tax credits	(1.80%)	(2.50%)		(4.20%)
State taxes, net of federal benefit	(3.60%)	(7.20%)		(3.90%)
Stock-based compensation	1.00%	0.80%		0.70%
Uncertain tax position reserves	0.40%	0.50%		6.30%
Other	(0.40%)	(0.10%)		0.20%
Change in deferred tax asset valuation allowance	25.40%	29.50%		21.90%
Effective income tax rate	0.00%	0.00%		0.00%

[1] Prior period amounts have been retrospectively adjusted to reflect the effects of the Transaction.