Collaboration Profit and Loss - Additional Information (Detail) - Nestle Health Science [Member] - 2021 License Agreement [Member] - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023	Jul. 21, 2021	Jul. 01, 2021
Business Acquisition [Line Items]
Transaction price allocated under collaborative arrangement						$ 35,500
Topic 808 [Member]
Business Acquisition [Line Items]
Transaction price allocated under collaborative arrangement							$ 35,500
Topic 808 [Member] | Total Liabilities [Member]
Business Acquisition [Line Items]
Transaction price allocated under collaborative arrangement							$ 35,500
Topic 808 [Member] | Accrued Expenses and Other Current Liabilities [Member]
Business Acquisition [Line Items]
Transaction price allocated under collaborative arrangement	$ 10,064		$ 10,064		$ 10,064
Research and Development Expenses [Member] | Topic 808 [Member]
Business Acquisition [Line Items]
Cost associated with pre-launch activities	0	$ 645	0	$ 1,446
General and Administrative Expenses [Member] | Topic 808 [Member]
Business Acquisition [Line Items]
Cost associated with pre-launch activities	$ 0	$ 1,539	$ 0	$ 4,242