Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Mar. 31, 2024	Dec. 31, 2023
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 71,511	$ 73,595
Less: Accumulated depreciation and amortization	(52,396)	(51,138)
Property and equipment, net	19,115	22,457
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	29,003	29,081
Computer Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,142	4,142
Furniture and Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	5,188	5,430
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	32,039	33,549
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 1,139	$ 1,393