Nature of the Business and Basis of Presentation - Additional Information (Detail) $ in Thousands			12 Months Ended
	Nov. 02, 2023 Employee	Oct. 29, 2023 Employee	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Nature Of Business And Basis Of Presentation [Line Items]
Entity incorporated month and year			2010-10
Entity incorporation, state or country code			DE
Reduction in workforce, percentage		41.00%
Number of positions eliminated | Employee	160	160
Accumulated deficit			$ (978,235)	$ (864,511)
Cash and cash equivalents			127,965	163,030
Net Income (Loss)			(113,724)	(250,157)	$ (65,578)
Net operating cash outflows			$ (117,354)	$ (228,816)	$ 6,688