DEFA14A 1 copy_of_definitive_addl_.htm DEFA14A DEFA14A



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SERES THERAPEUTICS Your Vote Counts! SERES THERAPEUTICS, INC. 2023 Annual Meeting Vote by June 21, 2023 11:59 PM ET SERES THERAPEUTICS, INC. 200 SIDNEY STREET CAMBRIDGE, MA 02139 You invested in SERES THERAPEUTICS, INC. and it’s time to vote! You have the right to vote on proposals being presented at the Annual Meeting. This is an important notice regarding the availability of proxy material for the stockholder meeting to be held on June 22, 2023. Get informed before you vote View the Notice and Proxy Statement and Annual Report online OR you can receive a free paper or email copy of the material(s) by requesting prior to June 8, 2023. If you would like to request a copy of the material(s) for this and/or future stockholder meetings, you may (1) visit, (2) call 1-800-579-1639 or (3) send an email to If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email copy. For complete information and to vote, visitwww.ProxyVote.comControl # Smartphone users Point your camera here and vote without entering a control number Vote Virtually at the Meeting* June 22, 2023 8:00 AM EDT Virtually at*Please check the meeting materials for any special requirements for meeting attendance.



THIS IS NOT A VOTABLE BALLOT Vote at This is an overview of the proposals being presented at the upcoming stockholder meeting. Please follow the instructions on the reverse side to vote these important matters. Voting Items 1. Election of Directors Nominees: 01) Stephen A. Berenson 02) Richard N. Kender 03) Claire M. Fraser, Ph.D. 2. Ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2023. 3. Approval, on an advisory (non-binding) basis, of the compensation of our named executive officers. 4. Approval of an amendment to our Restated Certificate of Incorporation to increase the number of authorized shares of Common Stock from 200,000,000 to 240,000,000. 5. Approval of an adjournment of the Annual Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Annual Meeting to approve Proposal 4. NOTE: To transact such other business as may properly come before the Annual Meeting or any continuation, postponement, or adjournment thereof. Board Recommends For For For For For Prefer to receive an email instead? While voting on,be sure to click “Delivery Settings”