Lessee term of operating sublease description.

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- Definition

Sub lease commencement date.

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- Definition

Transaction price allocated under collaborative arrangement

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Face amount or stated value per share of common stock.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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- Definition

The aggregate amount of receivables to be collected from related parties where one party can exercise control or significant influence over another party; including affiliates, owners or officers and their immediate families, pension trusts, and so forth, at the financial statement date. which are usually due within one year (or one business cycle).

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Portion of the carrying amount as of the balance sheet date of obligations due all related parties that is payable after one year or beyond the normal operating cycle if longer.

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The cash inflow from the additional capital contribution to the entity.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Reflects the sum of all other revenue and income realized from sales and other transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party during the period.

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Amount of selling, general and administrative expenses resulting from transactions, excluding transactions that are eliminated in consolidated or combined financial statements, with related party.

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No definition available.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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- Definition

Number of new stock issued during the period.

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Amount of sublease income excluding finance and operating lease expense.

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Related Party Transactions - Additional Information (Detail) - USD ($)		3 Months Ended	12 Months Ended
	Jun. 29, 2022	Mar. 31, 2022	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Feb. 29, 2016
Related Party Transaction [Line Items]
Collaboration revenue - related party			$ 7,128,000	$ 143,857,000	$ 11,897,000
Common stock, shares issued	8,738,243
Common stock, par value	$ 3.15		$ 0.001	$ 0.001
Proceeds from issuance of common stock	$ 27,525,000		$ 96,721,000	$ 0	243,748,000
Payment for the lease option			0	10,585,000
Nestle Health Science [Member]
Related Party Transaction [Line Items]
Collaboration revenue - related party			3,014,000	10,446,000	$ 11,897,000
Deferred revenue			94,713,000	97,728,000		$ 120,000,000
Payments under agreements with related party			0	0
Due from related party for the reimbursement of development costs			0	0
Nestle Health Science [Member] \| 2021 License Agreement [Member]
Related Party Transaction [Line Items]
Collaboration revenue - related party			4,114,000	133,411,000
Deferred revenue			1,976,000	6,089,000
Payments under agreements with related party			0	0
Due from related party for the reimbursement of development costs			0	0
Nestle Health Science [Member] \| 2021 License Agreement [Member] \| Accrued Expenses and Other Current Liabilities [Member]
Related Party Transaction [Line Items]
Transaction price allocated under collaborative arrangement			34,770,000	21,098,000
Nestle Health Science [Member] \| 2021 License Agreement [Member] \| Other Long-term Liabilities [Member]
Related Party Transaction [Line Items]
Transaction price allocated under collaborative arrangement			$ 0	10,585,000
Flagship Pioneering [Member]
Related Party Transaction [Line Items]
Proceeds from issuance of common stock	$ 27,525,000
Flagship Pioneering [Member] \| Sublease Agreement [Member]
Related Party Transaction [Line Items]
Lessee, term of operating sublease, description			The term of the sublease agreement commenced in July 2019 and ended in November 2021
Sub lease commencement date		2019-07
Cash received from related party transaction			$ 0	1,575,000
Flagship Pioneering [Member] \| Sublease Agreement [Member] \| Other Income [Member]
Related Party Transaction [Line Items]
Sublease income			0	$ 1,575,000
Flagship Pioneering [Member] \| Pledge and Utilization Agreement [Member]
Related Party Transaction [Line Items]
Payment for the lease option			$ 833,000