Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue:
Collaboration revenue - related party	$ 7,128	$ 143,857	$ 11,897
Type of Revenue [Extensible List]	us-gaap:LicenseAndServiceMember	us-gaap:LicenseAndServiceMember	us-gaap:LicenseAndServiceMember
Grant revenue	$ 0	$ 1,070	$ 4,157
Collaboration revenue	0	0	17,161
Total revenue	7,128	144,927	33,215
Operating expenses:
Research and development expenses	172,920	141,891	90,570
General and administrative expenses	79,694	69,261	30,775
Collaboration (profit) loss sharing - related party	1,004	(1,732)	0
Total operating expenses	253,618	209,420	121,345
Loss from operations	(246,490)	(64,493)	(88,130)
Other (expense) income:
Interest income	3,058	2,870	946
Interest expense	(6,020)	(2,910)	(2,924)
Other (expense) income	(705)	(1,045)	981
Total other (expense) income, net	(3,667)	(1,085)	(997)
Net loss	$ (250,157)	$ (65,578)	$ (89,127)
Net loss per share attributable to common stockholders, basic	$ (2.31)	$ (0.72)	$ (1.12)
Net loss per share attributable to common stockholders, diluted	$ (2.31)	$ (0.72)	$ (1.12)
Weighted average common shares outstanding, basic	108,077,043	91,702,866	79,789,220
Weighted average common shares outstanding, diluted	108,077,043	91,702,866	79,789,220
Other comprehensive loss:
Unrealized gain (loss) on investments, net of tax of $0	$ 49	$ (12)	$ (47)
Currency translation adjustment	(1)	(1)	0
Total other comprehensive income (loss)	48	(13)	(47)
Comprehensive loss	$ (250,109)	$ (65,591)	$ (89,174)