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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2022
Mar. 03, 2023
Jun. 30, 2022
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2022    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Trading Symbol MCRB    
Entity Registrant Name Seres Therapeutics, Inc.    
Entity Central Index Key 0001609809    
Entity Current Reporting Status Yes    
Current Fiscal Year End Date --12-31    
Entity Filer Category Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Entity Shell Company false    
Entity File Number 001-37465    
Entity Tax Identification Number 27-4326290    
Entity Address, Address Line One 200 Sidney Street – 4th Floor    
Entity Address, City or Town Cambridge    
Entity Address, State or Province MA    
Entity Address, Postal Zip Code 02139    
City Area Code 617    
Local Phone Number 945-9626    
Entity Public Float     $ 239,918,450
Entity Common Stock Shares Outstanding   126,076,391  
Entity Incorporation, State or Country Code DE    
Document Annual Report true    
Document Transition Report false    
Entity Well Known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Interactive Data Current Yes    
Title of 12(b) Security Common stock, par value $0.001 per share    
Security Exchange Name NASDAQ    
Documents Incorporated by Reference

Portions of the registrant’s definitive Proxy Statement relating to its 2023 Annual Meeting of Stockholders to be filed with the SEC within 120 days after the end of the fiscal year ended December 31, 2022 are incorporated herein by reference in Part III.

    
Auditor Firm ID 238    
Auditor Name PricewaterhouseCoopers LLP    
Auditor Location Boston, Massachusetts