Collaboration Revenue - Schedule of Revenue Recognized (Detail) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue recognized in the period from:
Amounts included in the contract liability at the beginning of the period	$ 1,216	$ 5,263	$ 2,709	$ 9,911

Contract with customer liability revenue recognized with related party.

No definition available.

Name:	mcrb_ContractWithCustomerLiabilityRevenueRecognizedWithRelatedParty
Namespace Prefix:	mcrb_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration