Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended				6 Months Ended
	Jun. 29, 2022	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Entity incorporated month and year			2010-10
Entity incorporation, state or country code						DE
Accumulated deficit		$ 735,713				$ 735,713		$ 614,354
Net Income (Loss) Attributable to Parent		(64,735)	$ (56,624)	$ (48,330)	$ (35,465)	(121,359)	$ (83,795)
Cash, cash equivalents and short and long-term investments		$ 195,795				195,795
Total net proceeds	$ 96,841					$ 96,841
Common stock issued	31,746,030	92,306,944				92,306,944		91,889,418
Common stock at a purchase price	$ 3.15	$ 0.001				$ 0.001		$ 0.001