Net Income (Loss) per Share - Basic and Diluted Net Income (Loss) per Share Attributable to Common Stockholders (Detail) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Numerator:
Net income (loss)	$ (56,624)	$ (35,465)
Income (loss) attributable to common stockholders - basic	$ (56,624)	$ (35,465)
Denominator:
Weighted-average shares outstanding	92,164,419	91,527,800
Net income (loss) per share applicable to common stockholders - basic	$ (0.61)	$ (0.39)
Numerator:
Net loss	$ (56,624)	$ (35,465)
Denominator:
Weighted Average Number of Shares Outstanding, Basic	92,164,419	91,527,800
Stock Options to Purchase Common Stock [Member]
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share:
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share	14,820,313	11,596,379
Unvested Restricted Stock Units [Member]
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share:
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share	1,582,641	287,853
Shares Issuable under ESPP [Member]
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share:
Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share	32,355	6,357