Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 60,904	$ 58,206
Less: Accumulated depreciation and amortization	(41,838)	(40,268)
Property and equipment, net	19,066	17,938
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	20,623	19,137
Computer Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	3,383	3,255
Furniture and Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	1,376	1,219
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	32,975	32,925
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 2,547	$ 1,670

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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