Lessee term of operating sublease description.

No definition available.

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- Definition

Sub lease commencement date.

+ References

No definition available.

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- Definition

Transaction price allocated under collaborative arrangement

+ References

No definition available.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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- Definition

The aggregate amount of receivables to be collected from related parties where one party can exercise control or significant influence over another party; including affiliates, owners or officers and their immediate families, pension trusts, and so forth, at the financial statement date. which are usually due within one year (or one business cycle).

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- Definition

Indicates (true false) whether sublessee has option to extend operating sublease.

+ References

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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- Definition

Reflects the sum of all other revenue and income realized from sales and other transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party during the period.

+ References

No definition available.

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- Definition

Amount of selling, general and administrative expenses resulting from transactions, excluding transactions that are eliminated in consolidated or combined financial statements, with related party.

+ References

No definition available.

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- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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- Definition

Amount of sublease income excluding finance and operating lease expense.

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Related Party Transactions - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Feb. 29, 2016
Related Party Transaction [Line Items]
Collaboration revenue - related party	$ 143,857,000	$ 11,897,000	$ 27,188,000
Sublease income	1,575,000	1,813,000	890,000
Nestle Health Science [Member]
Related Party Transaction [Line Items]
Collaboration revenue - related party	10,446,000	11,897,000	$ 27,188,000
Deferred revenue	97,728,000	108,174,000		$ 120,000,000
Payments under agreements with related party	0
Due from related party for the reimbursement of development costs	0
Nestle Health Science [Member] \| 2021 License Agreement [Member]
Related Party Transaction [Line Items]
Collaboration revenue - related party	133,411,000
Deferred revenue	6,089,000
Payments under agreements with related party	0
Due from related party for the reimbursement of development costs	0
Nestle Health Science [Member] \| 2021 License Agreement [Member] \| Accrued Expenses and Other Current Liabilities [Member]
Related Party Transaction [Line Items]
Transaction price allocated under collaborative arrangement	21,098,000
Nestle Health Science [Member] \| 2021 License Agreement [Member] \| Other Long-term Liabilities [Member]
Related Party Transaction [Line Items]
Transaction price allocated under collaborative arrangement	$ 10,585,000
Flagship Pioneering [Member] \| Sublease Agreement [Member]
Related Party Transaction [Line Items]
Lessee, term of operating sublease, description	The term of the sublease agreement commenced in July 2019 and ends on the last day of the 24th calendar month following commencement, with no option to extend
Sub lease commencement date	2019-07
Lessee, operating sublease, existence of option to extend	false
Cash received from related party transaction	$ 1,575,000	1,813,000
Flagship Pioneering [Member] \| Sublease Agreement [Member] \| Other Income [Member]
Related Party Transaction [Line Items]
Sublease income	$ 1,575,000	$ 1,813,000