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Commitments and Contingencies - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Nov. 30, 2018
Aug. 31, 2017
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Dec. 31, 2018
Commitments And Contingencies [Line Items]              
Operating sublease, right-of-use asset     $ 2,013,000   $ 2,013,000   $ 0
Operating lease right-of-use asset     3,003,000   3,003,000    
Operating lease costs     300,000 $ 200,000 600,000 $ 100,000  
Contingent liabilities     $ 0   $ 0   $ 0
Office and Laboratory Space              
Commitments And Contingencies [Line Items]              
Operating lease commencement year         2018-11    
Operating lease expiration year         2023-02    
Operating lease, option to extend, description         The Lease commenced in November 2018 and will expire in February 2023, however, the Company has the option to extend the Lease for a 12-month period.    
Operating lease, renewal term     12 months   12 months    
Operating lease right-of-use asset     $ 1,000,000   $ 1,000,000    
Operating lease, liabilities     $ 1,100,000   $ 1,100,000    
Operating lease, remaining term         3 years 9 months    
Estimated incremental borrowing rate to recognize lease liability, percentage     7.00%   7.00%    
Office and Laboratory Space | COI Pharmaceuticals, Inc              
Commitments And Contingencies [Line Items]              
Lessee, operating sublease, option to terminate, description         In November 2018, the Company amended the 2017 Sublease to provide the Company with a one-time right to terminate as of March 1, 2024, subject to certain conditions and fees.    
Lessee, operating sublease, termination date Mar. 01, 2024            
Lessee, operating sublease, expiration year 2027-02            
Operating sublease, right-of-use asset     $ 2,000,000   $ 2,000,000    
Operating sublease, aggregate lease liability     $ 2,100,000   $ 2,100,000    
Operating sublease, remaining term         7 years 8 months    
Estimated incremental borrowing rate to recognize lease liability, percentage     8.50%   8.50%    
California | Office and Laboratory Space | COI Pharmaceuticals, Inc              
Commitments And Contingencies [Line Items]              
Sublease entered date   2017-08