X0306 4 2021-01-29 0 0001609550 Inspire Medical Systems, Inc. INSP 0001412895 Phillips Bryan K C/O INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 GOLDEN VALLEY MN 55416 0 1 0 0 See remarks Common Stock 2021-01-29 4 A 0 2275 0 A 2275 D Employee Stock Option (Right to Buy) 201.51 2021-01-29 4 A 0 15000 0 A 2031-01-29 Common Stock 15000 15000 D Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest in four equal installments on each of the first through fourth anniversaries of January 29, 2021, subject to the Reporting Person's continued employment with the Issuer through each applicable vesting date. The option vests and becomes exercisable as to 25% of the underlying shares on the first anniversary of January 29, 2021 and the remaining 75% of the underlying shares in 36 equal monthly installments thereafter, subject to the Reporting Person's continuous employment with the Issuer through the relevant vesting dates. Senior Vice President, General Counsel, Secretary and Chief Compliance Officer /s/ Bryan K. Phillips 2021-02-02