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Research Collaboration Agreement and License Agreement (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Research Collaboration Agreement and License Agreement (Textual)      
Research and development expenses $ 5,348 $ 7,349 $ 6,042
License Agreement and Collaboration Agreement [Member]      
Research Collaboration Agreement and License Agreement (Textual)      
Total payment obligation 7,200,000    
Research and development expenses $ 1,600,000    
Research collaboration agreement expire date May 16, 2021