Loan Agreement with Kreos and Related Warrant to Purchase Ordinary Shares (Details) - USD ($) $ / shares in Units, $ in Thousands			1 Months Ended	12 Months Ended
	Jun. 09, 2017	Dec. 30, 2015	Nov. 20, 2018	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Loan Agreement with Kreos and Related Warrant to Purchase Ordinary Shares (Textual)
Proceeds from long term loan
Outstanding principal				7,000,000
Loss on extinguishment of debt						$ 313
warrant exercise agreements, description				On June 5, 2019 and June 6, 2019, the Company entered into warrant exercise agreements with certain institutional investors of warrants to purchase the Company's ordinary shares, pursuant to which, Kreos agreed to exercise in cash their November 2018 warrants at the existing exercise price of $7.50 per share. Under the exercise agreements, the Company also agreed to issue to Kreos new warrants to purchase up to 480,000 ordinary shares at an exercise price of $7.50 per share and exercise period of five years.
Interest expense				$ 1,500,000
Second Amendment [Member]
Loan Agreement with Kreos and Related Warrant to Purchase Ordinary Shares (Textual)
Interest payments, description			On November 20, 2018, the Company and Kreos entered into the Second Amendment to the Loan Agreement (the "Second Amendment"). In the Second Amendment, the Company agreed to repay $3.6 million to Kreos in satisfaction of all outstanding indebtedness under the Kreos Convertible Note and other related payments, including prepayment costs and end of loan payments and Kreos agreed to terminate the Kreos Convertible Note. The Company repaid Kreos the $3.6 million by issuing to Kreos 192,000 units and 288,000 pre-funded units at the applicable public offering prices for an aggregate price of $3.6 million (including the aggregate exercise price for the ordinary shares to be received upon exercise of the pre-funded warrants, assuming Kreos exercises all of the pre-funded warrants it purchased as part of the Company's public offering). The Company and Kreos also agreed to revise the principal and the repayment schedule under the Kreos Loan Agreement. The revised repayment schedule, effectively deferred an additional $1.1 million of payments that were due in 2018 and $2.8 million that were due in 2019 under the loan's prior repayment schedule, for total deferred payments of $3.9 million compared to the prior repayment schedule. Additionally, Kreos and the Company entered into the Kreos Warrant Amendment, which amended the exercise price of the warrant to purchase 6,679 ordinary shares currently held by Kreos from $241 to $7.5. The Second Amendment also made certain changes to the prepayment premiums under the Kreos Loan Agreement, tying them to the date of the Second Amendment
Secured Debt [Member]
Loan Agreement with Kreos and Related Warrant to Purchase Ordinary Shares (Textual)
Proceeds from long term loan		$ 2,000,000
Loan term		36 months
Annual interest rate		10.75%
Extended repayment term		36 months
Required proceeds from issuance of common stock required for repayment period to be extended		$ 2,000,000
Loan term initial period		24 months
Secured Debt [Member] | First Amendment [Member]
Loan Agreement with Kreos and Related Warrant to Purchase Ordinary Shares (Textual)
Outstanding principal	$ 17,200,000
Portion of principal subject to repayment extension	$ 3,000,000
Convertible debt, number of shares that may be converted in shares	100,946
Conversion price (in USD per share)	$ 3.17
Outstanding principal not subject to conversion	$ 14,200,000
Maturity term	Jun. 09, 2020