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Shareholders' Equity (Details 1) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2019
Dec. 31, 2018
Dec. 31, 2017
Number      
Beginning of the period 26,093    
Number, Granted 12,425    
Number, Exercised    
RSUs vested (27,618)    
RSUs forfeited (10,875)    
Number, Forfeited (7,170)    
End of the period 75,036 26,093  
Number, Options exercisable at the end of the period 45,530    
Average exercise price      
Beginning of the period $ 48.78    
Average exercise price, Granted 4.69    
Average exercise price, Exercised    
Average exercise price, Forfeited 18.42    
End of the period 42.60 $ 48.78  
Average exercise price, Options exercisable at the end of the period $ 55.80    
Average remaining contractual life (in years)      
Average remaining contractual life (in years), Options outstanding at the beginning of the period 6 years 4 months 13 days    
Average remaining contractual life (in years), Options exercisable at the end of the period 6 years 4 months 17 days    
Aggregate intrinsic value (in thousands)      
Aggregate intrinsic value (in thousands), Options outstanding $ 114    
Aggregate intrinsic value (in thousands) Options outstanding at the end of the year $ 230 $ 114  
Employee Stock Option and Restricted Stock Units RSUs [Member]      
Number      
Beginning of the period 72,655 51,074  
Number, Granted   26,497  
RSUs granted 87,436    
Number, Exercised [1]    
Number, Forfeited   (4,916)  
End of the period   72,655 51,074
Number, Options exercisable at the end of the period   41,308  
Average exercise price      
Beginning of the period $ 47.75 $ 67.25  
Average exercise price, Granted   27.25  
Average exercise price, Exercised [1]    
Average exercise price, Forfeited   138.5  
End of the period   47.75 $ 67.25
Average exercise price, Options exercisable at the end of the period   $ 59.75  
Average remaining contractual life (in years)      
Average remaining contractual life (in years), Options outstanding at the beginning of the period [2]   6 years 4 months 13 days 6 years 3 months 29 days
Average remaining contractual life (in years), Options exercisable at the end of the period [2]   4 years 2 months 30 days  
Aggregate intrinsic value (in thousands)      
Aggregate intrinsic value (in thousands), Options outstanding $ 8  
Aggregate intrinsic value (in thousands) Options outstanding at the end of the year   $ 8
Aggregate intrinsic value (in thousands), Options exercisable at the end of the period    
[1] During the fiscal year ended December 31, 2018, the aggregate number of ordinary shares that were issued pursuant to RSUs that became vested on a net basis was 13,615 ordinary shares.
[2] Calculation of weighted average remaining contractual term does not include the RSUs that were granted, which have an indefinite contractual term.