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General (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended 12 Months Ended
Mar. 27, 2019
Nov. 30, 2018
Nov. 20, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
May 10, 2016
General (Textual)                  
Accumulated deficit       $ (164,894)   $ (152,918) $ (131,220)    
Negative cash flow from operations       $ (11,225) $ (12,174) $ (14,774) $ (22,462) $ (26,747)  
Reverse share split ratio of 1-for-25                
Ordinary shares, par value (in NIS per share)       $ 0.25   $ 0.25 $ 0.25    
NIS [Member]                  
General (Textual)                  
Ordinary shares, par value (in NIS per share) $ 0.25                
Kreos [Member] | Second Amendment [Member]                  
General (Textual)                  
Agreed to pay outstanding indebtedness     $ 3,600            
Proceeds of public offering     $ 3,600            
Number of purchasing units     192,000            
Number of pre-funded units     288,000            
Aggregate price of public offering     $ 3,600            
Exercise price of warrant to purchase ordinary shares     6,679            
Kreos [Member] | Second Amendment [Member] | Minimum [Member]                  
General (Textual)                  
Exercise price of warrant to purchase ordinary shares per share     $ 7.50            
Kreos [Member] | Second Amendment [Member] | Maximum [Member]                  
General (Textual)                  
Exercise price of warrant to purchase ordinary shares per share     $ 241            
ATM Offering Program [Member]                  
General (Textual)                  
Number of shares issued and sold           49,882      
Average price           $ 27.25      
Gross proceeds amount           $ 1,400      
Aggregate amount of fees and offering expenses           1,100      
Aggregate amount of fees           236      
Maximum amount which can be raised under ATM offering program           $ 25,000     $ 25,000
Follow-on public offering [Member]                  
General (Textual)                  
Number of shares issued and sold   728,019              
Gross proceeds amount   $ 13,100              
Description of follow-on public offering   The Company completed its follow-on public offering in which the Company issued and sold 18,200,498 units, each consisting of one ordinary share and one warrant to purchase one ordinary share. Each unit was sold to the public at a price of $0.30 per unit, additionally the company issued and sold 26,259,332 pre-funded units, each unit was sold to the public at a price of $0.29 per unit. Each unit containing one pre-funded warrant with an exercise price of $0.01 per share and one warrant to purchase one ordinary share. The total gross proceeds received from the follow-on public offering, before deducting commissions, discounts and expenses, were $13.1 million. (including proceeds from the exercise of 2,267,284 pre-funded warrants at the closing of the offering).              
Public price per unit   $ 7.5              
Additionally issued and sold pre-funded units   26,259,332              
Additionally issued and sold public price per unit   $ 0.29              
Proceeds from exercise of pre-funded warrants   2,267,284              
Additional pre-funded warrants to purchase aggregate ordinary shares exercised           562,466      
Additional proceeds of pre-funded warrants           $ 140,617      
Underwriters warrants to purchase ordinary shares issued           106,680      
Underwriters warrants to purchase exercisable term           November 20, 2018 until November 15, 2023      
Underwriters warrants to purchase exercisable price per share           $ 9.375