Shareholders' Equity (Details 1) - USD ($) $ / shares in Units, $ in Thousands	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Share-based Payment Arrangement [Abstract]
Number Options outstanding at the beginning of the period	72,655
Number, Granted	12,425
Number, Exercised
Number, Forfeited	(5,371)
Number, Options outstanding at the end of the period	79,709	72,655
Number, Options exercisable at the end of the period	43,868
Average exercise price, Options outstanding at the beginning of the period	$ 47.7
Average exercise price, Granted	5.37
Average exercise price, Exercised
Average exercise price, Forfeited	45.93
Average exercise price, Options outstanding at the end of the period	41.19	$ 47.7
Average exercise price, Options exercisable at the end of the period	$ 56.49
Average remaining contractual life (in years), Options outstanding at the beginning of the period	6 years 9 months 18 days	6 years 4 months 13 days
Average remaining contractual life (in years), Options exercisable at the end of the period	4 years 11 months 15 days
Aggregate intrinsic value (in thousands), Options outstanding	$ 393	$ 114
Aggregate intrinsic value (in thousands), Options exercisable at the end of the period