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SHAREHOLDERS' EQUITY (Details 4)
9 Months Ended
Sep. 30, 2020
$ / shares
shares
Class of Warrant or Right [Line Items]  
Warrants outstanding 10,304,914
Warrants outstanding and exercisable 10,304,914
December 31, 2015 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 4,771 [1]
Exercise price per warrant | $ / shares $ 7.500 [1]
Warrants outstanding and exercisable 4,771 [1]
Contractual term Dec. 30, 2025 [1]
November 1, 2016 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 97,496 [2]
Exercise price per warrant | $ / shares $ 118.750 [2]
Warrants outstanding and exercisable 97,496 [2]
Contractual term Nov. 01, 2021 [2]
December 28, 2016 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 1,908 [3]
Exercise price per warrant | $ / shares $ 7.500 [3]
Warrants outstanding and exercisable 1,908 [3]
Contractual term Dec. 30, 2025 [3]
November 20, 2018 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 126,839 [4]
Exercise price per warrant | $ / shares $ 7.500 [4]
Warrants outstanding and exercisable 126,839 [4]
Contractual term Nov. 20, 2023 [4]
November 20, 2018 One [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 106,680 [5]
Exercise price per warrant | $ / shares $ 9.375 [5]
Warrants outstanding and exercisable 106,680 [5]
Contractual term Nov. 15, 2023 [5]
February 25, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 45,600 [6]
Exercise price per warrant | $ / shares $ 7.187 [6]
Warrants outstanding and exercisable 45,600 [6]
Contractual term Feb. 21, 2024 [6]
April 5, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 408,457 [7]
Exercise price per warrant | $ / shares $ 5.140 [7]
Warrants outstanding and exercisable 408,457 [7]
Contractual term Oct. 07, 2024 [7]
April 5, 2019 One [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 49,015 [8]
Exercise price per warrant | $ / shares $ 6.503 [8]
Warrants outstanding and exercisable 49,015 [8]
Contractual term Apr. 03, 2024 [8]
June 5, 2019 and June 6, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 1,464,665 [9]
Exercise price per warrant | $ / shares $ 7.500 [9]
Warrants outstanding and exercisable 1,464,665 [9]
Contractual term Jun. 05, 2024 [9]
June 5, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 87,880 [10]
Exercise price per warrant | $ / shares $ 9.375 [10]
Warrants outstanding and exercisable 87,880 [10]
Contractual term Jun. 05, 2024 [10]
June 12, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 416,667 [11]
Exercise price per warrant | $ / shares $ 6.000 [11]
Warrants outstanding and exercisable 416,667 [11]
Contractual term Dec. 12, 2024 [11]
June 10, 2019 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 50,000 [12]
Exercise price per warrant | $ / shares $ 7.500 [12]
Warrants outstanding and exercisable 50,000 [12]
Contractual term Jun. 10, 2024 [12]
February 10, 2020 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 4,343,500 [13]
Exercise price per warrant | $ / shares $ 1.250 [13]
Warrants outstanding and exercisable 4,343,500 [13]
Contractual term Feb. 10, 2025 [13]
February 10, 2020 One [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 336,000 [14]
Exercise price per warrant | $ / shares $ 1.5625 [14]
Warrants outstanding and exercisable 336,000 [14]
Contractual term Feb. 10, 2025 [14]
July 6, 2020 [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 2,469,139 [15]
Exercise price per warrant | $ / shares $ 1.76 [15]
Warrants outstanding and exercisable 2,469,139 [15]
Contractual term Jul. 02, 2025 [15]
July 6, 2020 One [Member]  
Class of Warrant or Right [Line Items]  
Warrants outstanding 296,297 [16]
Exercise price per warrant | $ / shares $ 2.2781 [16]
Warrants outstanding and exercisable 296,297 [16]
Contractual term Jul. 02, 2025 [16]
[1] Represents warrants for ordinary shares issuable upon an exercise price of $7.5 per share, which were granted on December 31, 2015 to Kreos Capital V (Expert) Fund Limited, or Kreos, in connection with a loan made by Kreos to us and are currently exercisable (in whole or in part) until the earlier of (i) December 30, 2025 or (ii) immediately prior to the consummation of a merger, consolidation, or reorganization of us with or into, or the sale or license of all or substantially all the assets or shares of us to, any other entity or person, other than a wholly-owned subsidiary of us, excluding any transaction in which our shareholders prior to the transaction will hold more than 50% of the voting and economic rights of the surviving entity after the transaction. None of these warrants had been exercised as of September 30, 2020
[2] Represents warrants issued as part of our follow-on offering in November 2016. At any time, the board of directors may reduce the exercise price of the warrants to any amount and for any period of time it deems appropriate.
[3] Represents common warrants that were issued as part of the $8.0 million drawdown under the Loan Agreement which occurred on December 28, 2016. See footnote 1 for exercisability terms.
[4] Represents common warrants that were issued as part of our follow-on offering in November 2018.
[5] Represents common warrants that were issued to the underwriters as compensation for their role in our follow-on offering in November 2018.
[6] Represents warrants that were issued to the exclusive placement agent as compensation for its role in our follow-on offering in February 2019.
[7] Represents warrants that were issued to certain institutional purchasers in a private placement in our registered direct offering of ordinary shares in April 2019.
[8] Represents warrants that were issued to the placement agent as compensation for its role in our April 2019 registered direct offering.
[9] Represents warrants that were issued to certain institutional investors in a warrant exercise agreement on June 5, 2019 and June 6, 2019, respectively.
[10] Represents warrants that were issued to the placement agent as compensation for its role in our June 2019 warrant exercise agreement and concurrent private placement of warrants.
[11] Represents warrants that were issued to certain institutional purchasers in a private placement in the Company's registered direct offering of ordinary shares in June 2019.
[12] Represents warrants that were issued to the placement agent as compensation for its role in our June 2019 registered direct offering and concurrent private placement of warrants.
[13] Represents warrants that were issued to certain institutional purchasers in a private placement in the Company's best efforts offering of ordinary shares in February 2020.
[14] Represents warrants that were issued to the placement agent as compensation for its role in the Company's February 2020 best efforts offering.
[15] Represents warrants that were issued to certain institutional purchasers in a private placement in our registered direct offering of ordinary shares in July 2020.
[16] Represents warrants that were issued to the placement agent as compensation for its role in the Company's July 2020 registered direct offering.