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Equity incentive plans - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2018
Options Outstanding      
Outstanding, beginning balance (in shares) 18,932,979    
Outstanding, ending balance (in shares) 20,342,259 18,932,979  
2021 Stock incentive Plan      
Options Outstanding      
Outstanding, beginning balance (in shares) 18,532,979    
Granted (in shares) 5,529,439    
Exercised (in shares) (2,923,761)    
Canceled (in shares) (1,196,398)    
Outstanding, ending balance (in shares) 19,942,259 18,532,979  
Weighted Average Exercise Price      
Outstanding, beginning balance (in USD per share) $ 5.12    
Granted (in USD per share) 21.97    
Exercised (in USD per share) 3.75    
Canceled (in USD per share) 10.02    
Outstanding, ending balance (in USD per share) $ 9.70 $ 5.12  
Outstanding, Weighted Average Remaining Contractual Term (in years) 8 years 1 month 20 days 8 years 5 months 15 days  
Outstanding, Aggregate Intrinsic Value $ 226,350 $ 123,166  
Vested and Expected to Vest, Awards Outstanding (in shares) 19,942,259    
Vested and Expected to Vest, Weighted Average Exercise Price (in USD per shares) $ 9.70    
Vested and Expected to Vest, Weighted Average Remaining Contractual Term (in years) 8 years 1 month 20 days    
Vested and Expected to Vest, Aggregate Intrinsic Value $ 226,350    
Exercisable, Awards Outstanding (in shares) 8,002,666    
Exercisable, Weighted Average Exercise Price (in USD per share) $ 4.77    
Exercisable, Weighted Average Remaining Contractual Term (in years) 7 years 4 months 28 days    
Exercisable, Aggregate Intrinsic Value $ 118,769    
Performance-Based Awards      
Options Outstanding      
Granted (in shares)   350,000 50,000
Performance-Based Awards | Amended and Restated 2010 Equity Incentive Plan      
Options Outstanding      
Outstanding, beginning balance (in shares) 400,000    
Granted (in shares) 0    
Exercised (in shares) 0    
Canceled (in shares) 0    
Outstanding, ending balance (in shares) 400,000 400,000  
Weighted Average Exercise Price      
Outstanding, beginning balance (in USD per share) $ 10.12    
Granted (in USD per share) 0    
Exercised (in USD per share) 0    
Canceled (in USD per share) 0    
Outstanding, ending balance (in USD per share) $ 10.12 $ 10.12  
Outstanding, Weighted Average Remaining Contractual Term (in years) 8 years 7 months 6 days 9 years 7 months 6 days  
Outstanding, Aggregate Intrinsic Value $ 3,768 $ 660  
Vested and Expected to Vest, Awards Outstanding (in shares) 400,000    
Vested and Expected to Vest, Weighted Average Exercise Price (in USD per shares) $ 10.12    
Vested and Expected to Vest, Weighted Average Remaining Contractual Term (in years) 8 years 7 months 6 days    
Vested and Expected to Vest, Aggregate Intrinsic Value $ 3,768    
Exercisable, Awards Outstanding (in shares) 2,083    
Exercisable, Weighted Average Exercise Price (in USD per share) $ 3.06    
Exercisable, Weighted Average Remaining Contractual Term (in years) 6 years 6 months 29 days    
Exercisable, Aggregate Intrinsic Value $ 34