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Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Income Statement [Abstract]        
Revenues $ 0 $ 0 $ 0 $ 0
Operating expenses:        
Research and development 3,715,379 2,371,058 7,243,529 4,248,236
General and administrative 1,267,364 1,206,995 2,707,876 2,597,233
Total operating expenses 4,982,743 3,578,053 9,951,405 6,845,469
Loss from operations (4,982,743) (3,578,053) (9,951,405) (6,845,469)
Other income (expense):        
Change in fair value of debt conversion feature liability 570,676 412,050 848,374 508,597
Amortization of debt discount (336,656) (524,977) (767,883) (925,634)
Amortization of financing costs (421,781)   (519,960)  
Interest expense, net (1,130) (1,813) (2,660) (17,275)
Total other income (expense), net (188,891) (114,740) (442,129) (434,312)
Net loss (5,171,634) (3,692,793) (10,393,534) (7,279,781)
Other comprehensive gain (loss), net of tax:        
Unrealized gain (loss) on securities 1,500 (6,591) 893 584
Comprehensive loss $ (5,170,134) $ (3,699,384) $ (10,392,641) $ (7,279,197)
Basic and diluted net loss per share $ (0.21) $ (0.22) $ (0.45) $ (0.56)
Weighted-average shares used to compute basic and diluted net loss per share 24,118,887 17,105,374 23,240,782 13,060,576