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    <periodOfReport>2021-01-12</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001594466</issuerCik>
        <issuerName>Pioneer PE Holding LLC</issuerName>
        <issuerTradingSymbol>PE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001606914</rptOwnerCik>
            <rptOwnerName>Sheffield Bryan</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>303 COLORADO STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>AUSTIN</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>78701</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
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            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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                    <value>By Sharoll M. Sheffield 2012 Irrevocable Trust</value>
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        <nonDerivativeTransaction>
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                    <value>By Spouse</value>
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        <nonDerivativeTransaction>
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                </underlyingSecurityShares>
            </underlyingSecurity>
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                <directOrIndirectOwnership>
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                    <value>By Bryan S. Sheffield Spousal Lifetime Access Trust</value>
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                <directOrIndirectOwnership>
                    <value>I</value>
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                    <value>By Sharoll M. Sheffield 2012 Irrevocable Trust</value>
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    <footnotes>
        <footnote id="F1">On January 12, 2021, pursuant to the Agreement and Plan of Merger dated as of October 20, 2020 (as amended, the &quot;merger agreement&quot;), (i) a direct wholly owned subsidiary of Pioneer Natural Resources Company (&quot;Pioneer&quot;) merged with and into Parsley Energy, Inc. (&quot;Parsley&quot;), with Parsley surviving the merger as a direct wholly owned subsidiary of Pioneer (the &quot;first merger&quot; and the surviving entity, the &quot;surviving corporation&quot;); (ii) simultaneously with the first merger, another direct wholly owned subsidiary of Pioneer merged with and into Parsley Energy, LLC, a majority-owned subsidiary of Parsley (&quot;Parsley LLC&quot;), with Parsley LLC surviving the merger as a direct and indirect wholly owned subsidiary of Pioneer (the &quot;Opco merger&quot;);</footnote>
        <footnote id="F2">(cont'd from Footnote 1) and (iii) immediately following the first merger and the Opco merger, the surviving corporation merged with and into a third direct wholly owned subsidiary of Pioneer (&quot;Merger Sub LLC&quot;), with Merger Sub LLC surviving the merger as a direct wholly owned subsidiary of Pioneer (together with the first merger and the Opco merger, the &quot;mergers&quot;). Pursuant to the merger agreement, (i) each eligible share of Class A common stock issued and outstanding immediately prior to the effective time of the first merger was converted into the right to receive 0.1252 shares of Pioneer common stock; (ii) each unit representing membership interests in Parsley LLC was converted into the right to receive 0.1252 shares of Pioneer common stock; and (iii) each corresponding share of Class B common stock was automatically cancelled for no additional consideration. On January 11, 2021 (the day prior to the mergers), the closing price of one share of Pioneer common stock was $131.42.</footnote>
        <footnote id="F3">Mr. Sheffield serves as the investment trustee of the Bryan S. Sheffield Spousal Lifetime Access Trust, and Mr. Sheffield and his children are beneficiaries of the Bryan S. Sheffield Spousal Lifetime Access Trust.</footnote>
        <footnote id="F4">Mr. Sheffield's spouse serves as the investment trustee of the Sharoll M. Sheffield 2012 Irrevocable Trust, and Mr. Sheffield's spouse and children are beneficiaries of the Sharoll M. Sheffield 2012 Irrevocable Trust.</footnote>
        <footnote id="F5">Each share of Class B common stock has no economic rights but entitles its holder to one vote on all matters to be voted on by stockholders generally.</footnote>
        <footnote id="F6">Prior to the consummation of the mergers and subject to the terms of the Fourth Amended and Restated Limited Liability Company Agreement of Parsley LLC, dated July 22, 2019, by and among Parsley LLC and the members thereof, the membership units of Parsley LLC (together with a corresponding number of shares of Class B common stock) were exchangeable from time to time for Class A common stock at an exchange ratio of one share of Class A common stock for each membership unit of Parsley LLC (and the corresponding share of Class B common stock).</footnote>
    </footnotes>

    <remarks>Executive Chairman</remarks>

    <ownerSignature>
        <signatureName>/s/ Bryan Sheffield, by Colin Roberts, as Attorney-in-Fact</signatureName>
        <signatureDate>2021-01-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
