Income Taxes - Deferred Income Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Income Taxes
Valuation allowance	$ 747,090	$ 639,510
Deferred tax assets
Net operating loss carryforwards	395,139	399,287
Research and development tax credit carryforwards	90,759	67,035
Capitalized research costs	173,991	95,923
Reserves and accruals	23,928	34,898
Lease liabilities	26,649	19,339
Stock based compensation	47,864	29,005
Intangible assets	8,846	3,809
Other	5,583	5,640
Total deferred tax assets before valuation allowance	772,759	654,936
Less: valuation allowance	(747,090)	(639,510)
Total deferred tax assets after valuation allowance	25,669	15,426
Deferred tax liabilities
Fixed assets	(4,164)	(1,524)
Right-of-use lease assets	(21,505)	(13,902)
Total deferred tax liabilities	(25,669)	(15,426)
Net deferred tax assets