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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Operating activities:    
Net loss $ (136,655) $ (356,770)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Depreciation and amortization 23,178 17,186
Expensed in-process research and development   2,679
Amortization of premiums and accretion of purchase discounts on investment securities (633) 1,929
Stock-based compensation 202,502 142,376
Non-cash lease expense 11,169 11,011
Non-cash expense recovery (80)  
Amortization of debt discount and issuance cost 991 966
Foreign exchange adjustment 356 265
Non-cash interest expense 2,680 85
Changes in operating assets and liabilities:    
Accounts receivable (28,587) (10,762)
Inventory (7,965) (6,669)
Prepaid expenses and other assets 13,663 7,356
Accounts payable 10,841 (8,951)
Accrued compensation 27,265 15,177
Operating lease liabilities (12,484) (8,424)
Other accrued liabilities (22,526) (2,072)
Deferred revenue (938) 5,268
Cash provided by (used in) operating activities 82,777 (189,350)
Investing activities:    
Purchases of investments (122,010)  
Proceeds from sale of investments 24,822  
Proceeds from maturity of investments 307,400 173,500
Purchases of property and equipment, net (48,305) (29,147)
Investment in related party (2,670)  
Cash paid for acquisition of intangible assets (10,495)  
Cash provided by investing activities 148,742 144,353
Financing activities:    
Proceeds from exercise of stock options 10,368 3,501
Proceeds from the issuance of common stock under the employee stock purchase plan 8,862 8,674
Proceeds from public offering, net of issuance cost   235,441
Cash provided by financing activities 19,230 247,616
Net change in cash, cash equivalents and restricted cash 250,749 202,619
Cash, cash equivalents and restricted cash, beginning of period 642,095 466,091
Cash, cash equivalents and restricted cash, end of period 892,844 668,710
Supplemental disclosure of cash flow information:    
Cash paid for interest 6,785 6,907
Non-cash investing and financing activities:    
Purchases of property and equipment in accounts payable and accruals 854 (1,168)
Acquisition of warrants and warrant receivable 9,424  
Amounts accrued for acquisition of intangible assets 1,400  
Issuance of common stock for IPR&D acquisition   14,435
Issuance of common stock for bonuses 24,071 19,771
Stock-based compensation included in capitalized software development costs $ 1,729 $ 520