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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Common stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Total
Balance at Dec. 31, 2022 $ 11 $ 2,664,730 $ (16,362) $ (1,942,635) $ 705,744
Balance (in shares) at Dec. 31, 2022 111,255        
Issuance of common stock upon exercise of stock options   3,501     3,501
Issuance of common stock upon exercise of stock options (in shares) 265        
Issuance of common stock under the employee stock purchase plan   8,674     8,674
Issuance of common stock under the employee stock purchase plan (in shares) 219        
Issuance of stock for bonuses   19,771     19,771
Issuance of stock for bonuses (in shares) 349        
Issuance of common stock for IPR&D milestone   14,435     14,435
Issuance of common stock for IPR&D milestone (in shares) 336        
Vesting of restricted stock units (in shares) 2,016        
Stock based compensation   142,896     142,896
Unrealized gain on available-for sale securities     10,966   10,966
Issuance of common stock for public offering, net   235,441     235,441
Issuance of common stock for public offering, net (in shares) 4,550        
Net loss       (356,770) (356,770)
Balance at Sep. 30, 2023 $ 11 3,089,448 (5,396) (2,299,405) 784,658
Balance (in shares) at Sep. 30, 2023 118,990        
Balance at Jun. 30, 2023 $ 11 2,795,714 (9,203) (2,190,375) 596,147
Balance (in shares) at Jun. 30, 2023 114,051        
Issuance of common stock upon exercise of stock options   562     562
Issuance of common stock upon exercise of stock options (in shares) 48        
Vesting of restricted stock units (in shares) 341        
Stock based compensation   57,731     57,731
Unrealized gain on available-for sale securities     3,807   3,807
Issuance of common stock for public offering, net   235,441     235,441
Issuance of common stock for public offering, net (in shares) 4,550        
Net loss       (109,030) (109,030)
Balance at Sep. 30, 2023 $ 11 3,089,448 (5,396) (2,299,405) 784,658
Balance (in shares) at Sep. 30, 2023 118,990        
Balance at Dec. 31, 2023 $ 11 3,145,837 (3,085) (2,377,436) $ 765,327
Balance (in shares) at Dec. 31, 2023 119,581       119,581
Issuance of common stock upon exercise of stock options   10,368     $ 10,368
Issuance of common stock upon exercise of stock options (in shares) 1,325        
Issuance of common stock under the employee stock purchase plan   8,862     8,862
Issuance of common stock under the employee stock purchase plan (in shares) 263        
Issuance of stock for bonuses   24,071     24,071
Issuance of stock for bonuses (in shares) 270        
Vesting of restricted stock units $ 1       1
Vesting of restricted stock units (in shares) 2,698        
Stock based compensation   204,231     204,231
Unrealized gain on available-for sale securities     2,320   2,320
Net loss       (136,655) (136,655)
Balance at Sep. 30, 2024 $ 12 3,393,369 (765) (2,514,091) $ 878,525
Balance (in shares) at Sep. 30, 2024 124,137       124,137
Balance at Jun. 30, 2024 $ 12 3,320,365 (1,358) (2,482,499) $ 836,520
Balance (in shares) at Jun. 30, 2024 123,365        
Issuance of common stock upon exercise of stock options   1,720     1,720
Issuance of common stock upon exercise of stock options (in shares) 247        
Vesting of restricted stock units (in shares) 525        
Stock based compensation   71,284     71,284
Unrealized gain on available-for sale securities     593   593
Net loss       (31,592) (31,592)
Balance at Sep. 30, 2024 $ 12 $ 3,393,369 $ (765) $ (2,514,091) $ 878,525
Balance (in shares) at Sep. 30, 2024 124,137       124,137