Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Revenues
Total revenues	$ 439,758,000	$ 268,306,000	$ 1,220,850,000	$ 771,466,000
Cost and expenses
Research and development	96,931,000	77,235,000	274,677,000	237,714,000
Selling, general and administrative	214,154,000	154,742,000	606,397,000	456,877,000
Total cost and expenses	479,096,000	379,288,000	1,378,404,000	1,133,175,000
Loss from operations	(39,338,000)	(110,982,000)	(157,554,000)	(361,709,000)
Interest expense	(3,142,000)	(3,252,000)	(9,393,000)	(9,490,000)
Interest and other income, net	11,618,000	5,406,000	32,342,000	14,509,000
Loss before income taxes	(30,862,000)	(108,828,000)	(134,605,000)	(356,690,000)
Income tax expense	(730,000)	(202,000)	(2,050,000)	(80,000)
Net loss	(31,592,000)	(109,030,000)	(136,655,000)	(356,770,000)
Unrealized gain on available-for-sale securities, net of tax	593,000	3,807,000	2,320,000	10,966,000
Comprehensive loss	$ (30,999,000)	$ (105,223,000)	$ (134,335,000)	$ (345,804,000)
Net loss per share (Note 12):
Basic (in dollars per share)	$ (0.26)	$ (0.95)	$ (1.12)	$ (3.14)
Diluted (in dollars per share)	$ (0.26)	$ (0.95)	$ (1.12)	$ (3.14)
Weighted-average number of shares used in computing basic and diluted net loss per share:
Basic (in shares)	123,775	115,171	122,486	113,559
Diluted (in shares)	123,775	115,171	122,486	113,559
Product
Revenues
Total revenues	$ 436,127,000	$ 265,218,000	$ 1,212,163,000	$ 761,271,000
Cost and expenses
Cost of revenues	167,657,000	146,962,000	496,340,000	437,524,000
Licensing and other
Revenues
Total revenues	3,631,000	3,088,000	8,687,000	10,195,000
Cost and expenses
Cost of revenues	$ 354,000	$ 349,000	$ 990,000	$ 1,060,000