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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Common stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Total
Balance at Dec. 31, 2022 $ 11 $ 2,664,730 $ (16,362) $ (1,942,635) $ 705,744
Balance (in shares) at Dec. 31, 2022 111,255        
Issuance of common stock upon exercise of stock options   2,939     2,939
Issuance of common stock upon exercise of stock options (in shares) 217        
Issuance of common stock under the employee stock purchase plan   8,674     8,674
Issuance of common stock under the employee stock purchase plan (in shares) 219        
Issuance of common stock for bonuses   19,771     19,771
Issuance of common stock for bonuses (in shares) 349        
Issuance of common stock for IPR&D milestone   14,435     14,435
Issuance of common stock for IPR&D milestone (in shares) 336        
Vesting of restricted stock units (in shares) 1,675        
Stock based compensation   85,165     85,165
Unrealized gain on available-for sale securities     7,159   7,159
Net loss       (247,740) (247,740)
Balance at Jun. 30, 2023 $ 11 2,795,714 (9,203) (2,190,375) 596,147
Balance (in shares) at Jun. 30, 2023 114,051        
Balance at Mar. 31, 2023 $ 11 2,741,932 (11,798) (2,079,572) 650,573
Balance (in shares) at Mar. 31, 2023 113,359        
Issuance of common stock upon exercise of stock options   638     638
Issuance of common stock upon exercise of stock options (in shares) 48        
Issuance of common stock under the employee stock purchase plan   8,674     8,674
Issuance of common stock under the employee stock purchase plan (in shares) 219        
Vesting of restricted stock units (in shares) 425        
Stock based compensation   44,470     44,470
Unrealized gain on available-for sale securities     2,595   2,595
Net loss       (110,803) (110,803)
Balance at Jun. 30, 2023 $ 11 2,795,714 (9,203) (2,190,375) 596,147
Balance (in shares) at Jun. 30, 2023 114,051        
Balance at Dec. 31, 2023 $ 11 3,145,837 (3,085) (2,377,436) $ 765,327
Balance (in shares) at Dec. 31, 2023 119,581       119,581
Issuance of common stock upon exercise of stock options   8,648     $ 8,648
Issuance of common stock upon exercise of stock options (in shares) 1,078        
Issuance of common stock under the employee stock purchase plan   8,862     8,862
Issuance of common stock under the employee stock purchase plan (in shares) 263        
Issuance of common stock for bonuses   24,071     24,071
Issuance of common stock for bonuses (in shares) 270        
Vesting of restricted stock units $ 1       1
Vesting of restricted stock units (in shares) 2,173        
Stock based compensation   132,947     132,947
Unrealized gain on available-for sale securities     1,727   1,727
Net loss       (105,063) (105,063)
Balance at Jun. 30, 2024 $ 12 3,320,365 (1,358) (2,482,499) $ 836,520
Balance (in shares) at Jun. 30, 2024 123,365       123,365
Balance at Mar. 31, 2024 $ 12 3,241,326 (2,192) (2,445,035) $ 794,111
Balance (in shares) at Mar. 31, 2024 122,234        
Issuance of common stock upon exercise of stock options   2,182     2,182
Issuance of common stock upon exercise of stock options (in shares) 286        
Issuance of common stock under the employee stock purchase plan   8,862     8,862
Issuance of common stock under the employee stock purchase plan (in shares) 263        
Vesting of restricted stock units (in shares) 582        
Stock based compensation   67,995     67,995
Unrealized gain on available-for sale securities     834   834
Net loss       (37,464) (37,464)
Balance at Jun. 30, 2024 $ 12 $ 3,320,365 $ (1,358) $ (2,482,499) $ 836,520
Balance (in shares) at Jun. 30, 2024 123,365       123,365