Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Revenues
Total revenues	$ 413,351,000	$ 261,404,000	$ 781,092,000	$ 503,160,000
Cost and expenses
Research and development	89,109,000	78,173,000	177,746,000	160,479,000
Selling, general and administrative	197,965,000	152,508,000	392,243,000	302,135,000
Total cost and expenses	457,253,000	373,830,000	899,308,000	753,887,000
Loss from operations	(43,902,000)	(112,426,000)	(118,216,000)	(250,727,000)
Interest expense	(3,127,000)	(3,177,000)	(6,251,000)	(6,238,000)
Interest and other income, net	10,457,000	4,518,000	20,724,000	9,103,000
Loss before income taxes	(36,572,000)	(111,085,000)	(103,743,000)	(247,862,000)
Income tax (expense) benefit	(892,000)	282,000	(1,320,000)	122,000
Net loss	(37,464,000)	(110,803,000)	(105,063,000)	(247,740,000)
Unrealized gain on available-for-sale securities, net of tax	834,000	2,595,000	1,727,000	7,159,000
Comprehensive loss	$ (36,630,000)	$ (108,208,000)	$ (103,336,000)	$ (240,581,000)
Net loss per share (Note 12):
Basic (in dollars per share)	$ (0.30)	$ (0.97)	$ (0.86)	$ (2.20)
Diluted (in dollars per share)	$ (0.30)	$ (0.97)	$ (0.86)	$ (2.20)
Weighted-average number of shares used in computing basic and diluted net loss per share:
Basic (in shares)	122,853	113,690	121,834	112,734
Diluted (in shares)	122,853	113,690	121,834	112,734
Product
Revenues
Total revenues	$ 411,364,000	$ 258,256,000	$ 776,036,000	$ 496,053,000
Cost and expenses
Cost of revenues	169,850,000	142,808,000	328,683,000	290,562,000
Licensing and other
Revenues
Total revenues	1,987,000	3,148,000	5,056,000	7,107,000
Cost and expenses
Cost of revenues	$ 329,000	$ 341,000	$ 636,000	$ 711,000