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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Revenues    
Total revenues $ 367,741,000 $ 241,756,000
Cost and expenses    
Research and development 88,637,000 82,306,000
Selling, general and administrative 194,278,000 149,627,000
Total cost and expenses 442,055,000 380,057,000
Loss from operations (74,314,000) (138,301,000)
Interest expense (3,124,000) (3,061,000)
Interest and other income, net 10,267,000 4,585,000
Loss before income taxes (67,171,000) (136,777,000)
Income tax expense (428,000) (160,000)
Net loss (67,599,000) (136,937,000)
Unrealized gain on available-for-sale securities, net of tax 893,000 4,564,000
Comprehensive loss $ (66,706,000) $ (132,373,000)
Net loss per share (Note 12):    
Basic (in dollars per share) $ (0.56) $ (1.23)
Diluted (in dollars per share) $ (0.56) $ (1.23)
Weighted-average number of shares used in computing basic and diluted net loss per share:    
Basic (in shares) 120,814 111,767
Diluted (in shares) 120,814 111,767
Product    
Revenues    
Total revenues $ 364,672,000 $ 237,797,000
Cost and expenses    
Cost of revenues 158,833,000 147,754,000
Licensing and other    
Revenues    
Total revenues 3,069,000 3,959,000
Cost and expenses    
Cost of revenues $ 307,000 $ 370,000