Leases (Details) $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended
	Sep. 30, 2023 USD ($) ft²	Sep. 30, 2021 USD ($) ft²	Sep. 30, 2023 USD ($) ft²	Sep. 30, 2022 USD ($)	Sep. 30, 2023 USD ($) ft² lease item	Sep. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Lessee, Lease, Description [Line Items]
Operating lease liabilities, current portion included in other accrued liabilities | $	$ 11,038		$ 11,038		$ 11,038		$ 7,639
Operating lease liabilities, long-term portion | $	68,287		68,287		68,287		76,577
Operating lease liabilities | $	$ 79,325		$ 79,325		79,325		$ 84,216
Noncash operating activities related to right-of-use assets | $					$ 100	$ 22,100
Weighted average remaining lease term	6 years 11 months 8 days		6 years 11 months 8 days		6 years 11 months 8 days
Weighted average discount rate (as a percent)	6.67%		6.67%		6.67%
Lease expense | $			$ 3,600	$ 3,500	$ 11,000	10,000
Operating lease payments | $			$ 3,200	$ 1,700	$ 8,424	$ 7,207
Austin TX, Long-term Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	94,000		94,000		94,000
Number of office space locations | lease					2
Term of lease	132 months		132 months		132 months
First Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	32,500		32,500		32,500
Second Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	65,222		65,222		65,222
Corporate Headquarters Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	136,000		136,000		136,000
Number of office space locations | item					2
Term of lease	84 months		84 months		84 months
Renewal term of lease	5 years		5 years		5 years
"First Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations | ft²					88,000
"Second Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations | ft²					48,000
Corporate Headquarters Lease Amendment
Lessee, Lease, Description [Line Items]
Annual lease payment | $					$ 9,300
Term of lease	48 months		48 months		48 months
Tukwila, WA Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	10,000		10,000		10,000
Term of lease	62 months		62 months		62 months
Renewal term of lease	5 years		5 years		5 years
South San Francisco, CA Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	11,395		11,395		11,395
Annual lease payment | $					$ 900
Term of lease	36 months		36 months		36 months
Renewal term of lease	3 years		3 years		3 years
Pleasanton, CA Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	16,319		16,319		16,319
Annual lease payment | $	$ 500
Term of lease	60 months		60 months		60 months
Laboratory space in Canada
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		7,107
Annual lease payment | $		$ 200
Term of lease		24 months
Certain workspaces and storage spaces | Minimum
Lessee, Lease, Description [Line Items]
Term of lease	1 year		1 year		1 year
Certain workspaces and storage spaces | Maximum
Lessee, Lease, Description [Line Items]
Term of lease	5 years		5 years		5 years