Leases (Details) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Sep. 30, 2021 USD ($) ft²	Jun. 30, 2023 USD ($) ft²	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($) ft² item lease	Jun. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Lessee, Lease, Description [Line Items]
Operating lease liabilities, current portion included in other accrued liabilities | $		$ 10,435		$ 10,435		$ 7,639
Operating lease liabilities, long-term portion | $		71,093		71,093		76,577
Operating lease liabilities | $		$ 81,528		$ 81,528		$ 84,216
Weighted average remaining lease term		7 years 4 months 6 days		7 years 4 months 6 days
Weighted average discount rate (as a percent)		6.67%		6.67%
Lease expense | $		$ 3,700	$ 3,300	$ 7,500	$ 6,700
Operating lease payments | $		$ 3,000	$ 2,800	$ 5,196	5,528
Austin TX, Long-term Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		94,000		94,000
Number of office space locations | lease				2
Term of lease		132 months		132 months
First Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		32,500		32,500
Noncash operating activities related to right-of-use assets | $					$ 7,500
Second Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		65,222		65,222
Corporate Headquarters Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		136,000		136,000
Number of office space locations | item				2
Term of lease		84 months		84 months
Renewal term of lease		5 years		5 years
"First Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations | ft²				88,000
"Second Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations | ft²				48,000
Corporate Headquarters Lease Amendment
Lessee, Lease, Description [Line Items]
Annual lease payment | $				$ 9,300
Term of lease		48 months		48 months
Tukwila, WA Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		10,000		10,000
Term of lease		62 months		62 months
Renewal term of lease		5 years		5 years
South San Francisco, CA Lease
Lessee, Lease, Description [Line Items]
Office space (area) | ft²		11,395		11,395
Annual lease payment | $				$ 900
Term of lease		36 months		36 months
Renewal term of lease		3 years		3 years
Laboratory space in Canada
Lessee, Lease, Description [Line Items]
Office space (area) | ft²	7,107
Annual lease payment | $	$ 200
Term of lease	24 months
Certain workspaces and storage spaces | Minimum
Lessee, Lease, Description [Line Items]
Term of lease		1 year		1 year
Certain workspaces and storage spaces | Maximum
Lessee, Lease, Description [Line Items]
Term of lease		5 years		5 years