Leases (Details) $ in Thousands	1 Months Ended	3 Months Ended
	Sep. 30, 2021 USD ($) ft²	Mar. 31, 2023 USD ($) ft² item lease	Mar. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)
Lessee, Lease, Description [Line Items]
Operating lease liabilities, current portion included in other accrued liabilities | $		$ 9,308		$ 7,639
Operating lease liabilities, long-term portion | $		73,854		76,577
Operating lease liabilities | $		$ 83,162		$ 84,216
Noncash investing activities related to right-of-use assets | $			$ 7,500
Weighted average remaining lease term		7 years 4 months 6 days
Weighted average discount rate (as a percent)		6.67%
Lease expense | $		$ 3,800	3,300
Operating lease payments | $		$ 2,177	$ 2,765
Austin TX, Long-term Lease
Lessee, Lease, Description [Line Items]
Office space (area)		94,000
Number of office space locations | lease		2
Term of lease		132 months
First Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area)		32,500
Second Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area)		65,222
Corporate Headquarters Lease
Lessee, Lease, Description [Line Items]
Office space (area)		136,000
Number of office space locations | item		2
Term of lease		84 months
Renewal term of lease		5 years
"First Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations		88,000
"Second Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations		48,000
Corporate Headquarters Lease Amendment
Lessee, Lease, Description [Line Items]
Annual lease payment | $		$ 9,300
Term of lease		48 months
Tukwila, WA Lease
Lessee, Lease, Description [Line Items]
Office space (area)		10,000
Term of lease		62 months
Renewal term of lease		5 years
San Carlos, CA Sublease
Lessee, Lease, Description [Line Items]
Office space (area)		25,879
Term of lease		48 months
Sublease receivable | $		$ 1,900
San Carlos, CA Sublease Amendment | Rentable square feet surrendered in lease amendment
Lessee, Lease, Description [Line Items]
Office space (area)		25,879
South San Francisco, CA Lease
Lessee, Lease, Description [Line Items]
Office space (area)		11,395
Annual lease payment | $		$ 900
Term of lease		36 months
Renewal term of lease		3 years
Laboratory space in Canada
Lessee, Lease, Description [Line Items]
Office space (area)	7,107
Annual lease payment | $	$ 200
Term of lease	24 months