Revenue Recognition - Disaggregation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Total revenues	$ 820,222	$ 625,486	$ 391,005
United States
Disaggregation of Revenue [Line Items]
Total revenues	785,849	590,872	365,660
Americas, excluding U.S.
Disaggregation of Revenue [Line Items]
Total revenues	3,705	4,047	3,469
Europe, Middle East, India, and Africa
Disaggregation of Revenue [Line Items]
Total revenues	16,640	20,429	14,332
Asia Pacific and Other
Disaggregation of Revenue [Line Items]
Total revenues	14,028	10,138	7,544
Insurance carriers
Disaggregation of Revenue [Line Items]
Total revenues	690,754	492,563	300,220
Laboratory partners
Disaggregation of Revenue [Line Items]
Total revenues	94,910	100,019	58,196
Patients
Disaggregation of Revenue [Line Items]
Total revenues	34,558	32,904	32,589
Licensing and other
Disaggregation of Revenue [Line Items]
Total revenues	$ 22,915	$ 45,406	$ 13,128